High school Internship Programme-21 July-04 Aug 2025

We hosted high school interns within the scope of “Bilimle Tanış: Lise Öğrencileri Araştırma Staj Programı”. 

TUBITAK Science Meetings-06-13 May 2025

Within the scope of TÜBİTAK Science Talks, Assoc. Prof. Mehmet Özbil met with young students at "Üsküdar Şehit Gökhan Esen Ortaokulu" and "Düzce Zübeyde Hanım Mesleki ve Teknik Anadolu Lisesi".   

Special thanks to the esteemed teachers of Üsküdar Şehit Gökhan Esen Secondary School and especially Songül Hoca, the school vice principal Ahmet Hoca; Düzce Zübeyde Hanım Vocational and Technical Anatolian High School teachers and especially Demet Hoca and the school principal Salim Hoca for their great hospitality.

In both meetings, we exchanged information on computational biochemistry, biology, science, future career planning with young people who are the future of our country. I hope I have given our young people a new perspective. 

https://sehitgokhanesenookulu.meb.k12.tr/icerikler/tubitak-soylesileri-kapsaminda-doc-dr-mehmet-ozbil-ile-hesaplamali-biyokimya-alanina-bakis-konferansi-gerceklestirildi_16290672.html  

Award Announcement-23 January 2025

We received the most meaningful award from our own institution for the research carried out by our research group. Thanks to all the members of our group! 

Grant Acceptance-27 December 2024

Our TUBITAK 2515-COST Project Proposal titled "In silico Antigenic Characterization of Hemagglutinin Protein N-Glycosylation in Swine Influenza A (H3N2) Virus Family" has been awarded. The project aims to shed light on structural mechanisms of hemagglutunin (HA) protein glycosylation in the most frequently observed strains of Swine Influenza A virus recently through computational techniques. A detailed understanding of the mechanisms involved in glycosylation, which leads to increased viral infection and escape from antigenic neutralization, is critical for accurately predicting the future evolution of A/H3N2 viruses and being able to cope with the novel strains through vaccination or novel antibody therapies. Semanur Bulut, MSc student of our group, who also made a substantial contribution to the proposal, will be the investigator in the project. The project will align with the aims of "European Swine Influenza Network ESFLU - COST CA21132 project.  

Congress Attendance-04 May 2024

Assoc. Prof. Mehmet Özbil and group members Gizem Nur Duran and Semanur Bulut presented the research topics of our group in VII. GENÇOMÜ Student Congress, organized in Çanakkale 18 Mart University, Çanakkale, Turkiye, between 04-05 May 2024. Mehmet Özbil presented his talk titled "Biyoteknolojik Sorunlar için Hesapsal Kimya Yaklaşımları", Gizem Nur Duran presented her talk titled "Neisseria Meningitidis Bakterisinin Fe3+ İyonu Transfer Mekanizmasının Aydınlatılması", and Semanur Bulut presented her talk titled "Protein protein etkileşimlerinin hesapsal yaklaşımlarla incelenmesi". We have also led an in silico workshop dealing with protein-protein interactions. We thank GENÇOMÜ organization and their leader Prof. Dr. Tuğba Tümer for the great organization and great hospitality.  

Meeting Attendance-25 April 2024

Asoc. Prof. Mehmet Özbil presented few of the group's projects related with the effects of mutations in the presentations titled ‘Interpreting the effect of mutations on complexation and ion binding in enzymes’ in MC and WG Meeting of Cost Action CA21162 (COZYME) held in Zagreb, 24-26 April 2024. 

Graduation-23 February 2024

Another graduation at my CBG@GTU. Miray Çakıoroğlu has successfully presented her thesis titled "Computational Evolution of Molecularly Imprinted Monomers That Selectively Bind Alzheimer's Disease ApoE4 Protein" and received he M.Sc. degree. Congrats Miray, we wish you a successful career.

Grant Acceptance-18 September 2023

TÜSEB B-ARGE project grant proposal titled “Experimental and Computational Analysis of Anti-microbial and Anti-biofilm Characteristics of Green Hazelnut Husk Extracts Grown in Turkey” has been accepted. The project was developed by CBG@GTU group and Prof. Meltem Yeşilçimen Akbaş group. Assoc. Prof. Mehmet Özbil will be the principal investigator in the project. 

Congress Attendance-26 August 2023

Asoc. Prof. Mehmet Özbil presented findings from TUBITAK 1001 project in poster format titled ‘Understanding Fe3+ Theft by Neisseria Meningiditis: A Comprehensive Computational Study’ in EuChemS CompChem 2023 European Conference on Computational & Theoretical Chemisty “Exploring Molecular Space” held in Thessaloniki, 26-31 August 2023. 

Congress Attendance-26 August 2023

Sinem Nur Açıkgöz, MSc student, recieved with TÜBİTAK BİDEB 2210-C Thesis Award with her thesis proposal “Identification of phyto-phenol compounds for fighting against psoriasis and atopic dermatitis”. Congratulations Sinem! 

Grant Acceptance-21 March 2023

TÜBİTAK ARDEB 2209A grant proposal titled “In silico analysis of off-target binding of FX inhibitors and evaluation of their role in hemorrhage” has been accepted, in which Gökçe Kaymaz will be the researcher.  

Grant Acceptance-24 February 2022

TÜBİTAK ARDEB 1001 grant proposal titled “Search for novel potent drug molecules against N. meningitidis, responsible for meningitis, targetiing iron transfer mechanisms by pharmacophore based virtual screening” has been accepted, in which Assoc. Prof. Mehmet Özbil is the principal investigator.  

Grant Acceptance-01 December 2022

TÜBİTAK ARDEB 2209A grant proposal titled “Computational Investigation of Structural Changes on Frizzled 7 Mediated by Gα Protein Binding ” has been accepted, in which Görkem Güngör will be the researcher.  

IAPS-GTU Student Organization MD Workshop-26 October 2022

CBG@GTU research group met with undergraduate students, members of IAPS (International Association of Physics Students) student organization. We held Molecular Dynamics Workshop for 4 hours, which comprised of theoretical presentation and hands-on experience. We are happy to meet with undergraduate students and to help them gain experience in various fields of science! 

Graduate Visit-20 June 2022

Hasan Çubuk, one of our group graduates, visited our lab and talked about his doctoral studies on deep mutational scanning, machine learning based mutation analysis. He gave an inspiring lecture and shared his experiences. Hasan is currently a PhD candidate at the University of Edinburgh, Institute of Genetics and Cancer.  

Grant Acceptance-10 March 2022

Our Horizon 2020 Era-Net Cofund project proposal titled 'IPSUS-Smart Food Innovation: Implementation of plant and algae proteins from upcycled sources' for FOSC (Food Systems and Climate) and SUSFOOD2 2021 joint programme have been accepted! The project partners comprise of research groups from Univ. of Greenwich, Univ. of Parma, Ist. Sabahattin Zaim Univ., KEDGE Business School, Eole Nationale d'Agriculture de Meknes, Ghent University, Gelişim Univ., Biruni Univ., Gebze Technical Univ., and Kaanlar Food Co. Assist. Prof. Mehmet Özbil  will be one of the advisors on the project  

Grant Acceptance-15 February 2022

TÜBİTAK ARDEB 1001 grant proposal titled “Evaluation of the use of Holin protein as a biotechnological tool, which is a key molecule in the lysis mechanism of Lytic Bacteriophage K on S. aureus” has been accepted, in which Asst. Prof. Mehmet Özbil is a researcher.  

Congress Attendance-04 November 2021

Assist. Prof. Mehmet Özbil gave oral presentation titled ‘Neisseria meningitidis Transferrin Binding Protein A (TbpA) Rearranges Itself For Binding Human Transferrin Protein (hTf)’ at the ‘3. EuroAsia Biochemical Approaches and Technologies’ Congress held in Antalya, Turkey, 04-07 November 2021.  

Graduate Student Dissertation-03 August 2021

Our group member Gizem Nur Duran successfully defended her Master's Program Thesis. Congratulations Gizem and we wish you a very successful scientific career! 

Seminar EUROCC Lecture Series -01 April 2021

Asst. Prof. Mehmet Özbil gave lecture online for ULAKBIM TRUBA EUROCC Turkey Seminars titled "Utilization of Super Computing in Computational Biochemistry".  The speech was broadcasted live and around 130 attendance followed it live. After the speech brief GROMACS MD simulation tutorial was performed. The full length video can be found on Youtube ULAKBIM TV channel and at this link:

https://www.youtube.com/watch?v=IxqjzG3aUPs​ 

Grant Acceptance-15 March 2021

TÜBİTAK ARDEB 2209B grant proposal entitled “Computational Analysis of Epileptic Encephalopathy Disease Mutations” has been accepted, in which Sinem Nur Acikgoz and Nurgul Kaya Alper will be the researchers.  

Meeting with Fellow Students -27 November 2020

Asst. Prof. Mehmet Özbil met online with Chemistry major students from Istanbul Technical University. Mehmet Ozbil was also a graduate of  the same department (2007). The meeting was organized by ITU Kimya Kulubu, student organization, and drew an attendance around 60 people. We discussed future options for students and the path ahead of their prospective careers.  

Publication Alert-06 October 2020

The first COVID-19 related article by our group has been accepted for publication in Turkish Journal of  Chemistry, titled 'Comparison of clinically approved molecules on SARS-CoV-2 drug target proteins: A molecular docking study'.  

First Publication-01 September 2020

Our veteran group member Gizem Nur Duran's first article entitled "Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones" was published in Bio-organic Chemistry Journal. Congratulations Gizem and we are waiting for more to come. 

Grant Acceptance-06 June 2020

TÜBİTAK ARDEB 1001 grant proposal titled “Synthesis and in vitro-in vivo antibacterial efficacy evaluation of S.aureus-targeted nanoformulations loaded with vancomycin and oxacillin” has been accepted, in which Asst. Prof. Mehmet Özbil is a researcher. Budget of the project is 719.265 TL.

Congress Attendance-29 October 2019

Assist. Prof. Mehmet Özbil gave oral presentation entitled ‘Computational Construction of Neisseria Meningiditis Fe3+ Transfer Triple Complex’ and Gizem Nur Duran gave poster presentation entitled ‘Computational Construction TbpA - TbpB - hTF Triple Complex’ at the ‘2. EuroAsia Biochemical Approaches and Technologies’ Congress held in Antalya, Turkey, 26-29 October 2019.

Grant Acceptance-15 March 2019

TÜBİTAK ARDEB 2209A grant proposal entitled “Computational Analysis of Active Molecules-Rotavirus Proteins VP7 and VP8*” has been accepted, in which Alper Bulutoğlu will be the researcher. 

Grant Acceptance-11 September 2018

TÜBİTAK ARDEB 3501 grant proposal entitled “The Computational Studies on the Functioning  Mechanisms of Fe3+ Transfer by Neisseria Meningitidis” has been accepted, in which Asst. Prof. Mehmet Özbil is a researcher. Budget of the project is 224.446 TL.

Grant Acceptance-11 September 2018

TÜBİTAK ARDEB 1001 grant proposal entitled “Creating Turkey’s Haemophilia B Genetic Database and Identifying Genetic Variations in Haemophilia B Cases in Turkey” has been accepted, in which Asst. Prof. Mehmet Özbil is a researcher. Budget of the project is 358.580 TL.

Congress Attendance-07 September 2017

Asst. Prof. Mehmet Özbil gave poster presentation entitled ‘Chemical and Structural Effects of Inhibitor Molecules on Influenza A Virus M2 Protein Channel’ in the ​11th European Conference on Theoretical and Computational Chemistry held in Barcelona, 04-07 September 2017.

Graduation Project Presentations-09 May 2017

Our group members, Taylan Akyol, Gizem Duran, and Elif Özbay presented their exciting research projects on 9 May 2017, during Molecular Biology and Genetcis Department, Graduation Project poster presentations.

Workshop-05 May 2017

Molecular Docking Workshop was succesfully organized by the help of our group members at the ‘4th International GenArel Molecular Biology and Genetics Student Congress’, 5 May 2017.

Grant Acceptance-15 March 2019

TÜBİTAK ARDEB 2209A grant proposal entitled “Investigation of Structural Mechanism of Archeal Group-II Chaperonins (Themrosome) by Computational Tools” has been accepted, in which Taylan Deniz Akyol will be the researcher. 

Congress Attendance-13 October 2016

Asst. Prof. Mehmet Özbil gave oral presentation entitled ‘Investigating Inhibitor Binding Sites on Influenza A Virus M2 Protein’ in the 4th International BAU Drug Design Congress held in Istanbul, 13-15 October 2016. 

Grant Acceptance-23 November 2015

Asst. Prof. Mehmet Özbil’s research proposal, entitled ‘Understanding the Mechanism of Action and Inhibition of Infleunza A Virus M2 Protein Through Computational Approach’ has been rewarded by TUBITAK 2232 program.